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. 2008 Dec;125(4):570–590. doi: 10.1111/j.1365-2567.2008.02872.x

Figure 6.

Figure 6

Effect of B-cell-activating factor (BAFF) on CD40 expression in MLMA cells. (a) MLMA cells cultured with or without BAFF for 3 days were stained with fluorescein isothiocyanate (FITC)-labelled monoclonal antibody (mAb) against CD40 and analysed by flow cytometry as in Fig. 1. (b) The inhibitory effect of CD40 stimulation on apoptosis induction was examined. MLMA cells were treated with 500 ng/ml of CD40-ligand in the presence of 2·5 ng/ml of interleukin-4 to stimulate CD40. The effects of either stimulation of CD40 alone or simultaneous stimulation of CD40 and BAFF receptor on apoptosis similarly induced as in Fig. 2 were examined.