Table 1.
Cell lines |
||
---|---|---|
MDA468 | NQ16 | |
NQO1 activity (nmole DCPIP/min/mg protein) | NDa | 1061.4 ± 50.5 |
IC50 (nM) by MTT assay | 110.5 ± 13 | 6.1 ± 0.1b |
IC50 (nM) by SRB assay | 99.2 ± 6.7 | 7.4 ± 1.9b |
nd, non-detectable, < 5 nmole DCPIP/min/mg protein
A significant difference (P<0.01, Student's t-test) between IC50s for MDA468 and NQ16 cells.