. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Mol Pharmacol. 2008 Sep 15;74(6):1657–1665. doi: 10.1124/mol.108.050401

Table 1.

NQO1 activity and IC₅₀ values for RH1 in MDA468 parental cells and cells stably transfected with NQO1 (Clone NQ16).

	Cell lines
	MDA468	NQ16
NQO1 activity (nmole DCPIP/min/mg protein)	ND^a	1061.4 ± 50.5
IC₅₀ (nM) by MTT assay	110.5 ± 13	6.1 ± 0.1^b
IC₅₀ (nM) by SRB assay	99.2 ± 6.7	7.4 ± 1.9^b

nd, non-detectable, < 5 nmole DCPIP/min/mg protein

A significant difference (P<0.01, Student's t-test) between IC_50s for MDA468 and NQ16 cells.