Table 1.
Antigen expression in melanoma cell lines twenty nine hours following UV and/or gamma-irradiation*
| % Antigen Expression† | ||||||||
| gp100 | Tyrosinase | MART-1/MelanA | S100 | |||||
| Treatment | DM6 | DM93 | DM6 | DM93 | DM6 | DM93 | DM6 | DM93 |
| Non-irradiated | 98% | 100% | 25% | 98% | 90% | 90% | 100% | 100% |
| UV | 98% | 100% | < 1% | 5% | 70% | 85% | 100% | 100% |
| Gamma | 100% | 100% | 30% | 98% | 80% | 85% | 100% | 100% |
| UV + Gamma | 98% | 100% | < 1% | 1% | 75% | 85% | 100% | 100% |
* Melanoma cells were non-irradiated, gamma-irradiated (200 Gy), UV-irradiated (5 min), or both gamma-irradiated (200 Gy) and UV-irradiated (5 min).
†The percent of cells staining for gp100 expression, tyrosinase, MART-1/MelanA, and S100 expression was assessed by immunohistochemistry.