Table 3.
The prevalence of anti-thyroid peroxidase antibody (TPOAb) immunoglobulin G (IgG) subclasses in sera from patients with hypothyroidism, subclinical hypothyroidism and euthyroidism.
| Group | n | IgG1 positive n (%) | IgG2 positive n (%) | IgG3 positive n (%) | IgG4 positive n (%) |
|---|---|---|---|---|---|
| H | 66 | 47 (71·2) | 34 (51·5*,**) | 11 (16·7) | 48 (72·7*) |
| sH | 60 | 44 (73·3) | 20 (33·3*) | 10 (16·7) | 43 (71·7*) |
| E | 42 | 27 (64·3) | 5 (11·9) | 12 (28·6) | 20 (47·6) |
| Total | 168 | 118 (70·2) | 59 (35·1) | 33 (19·6) | 111 (66·1) |
*
P < 0·05 compared with E
**
P < 0·05 compared with sH. H, hypothyroidism; sH, subclinical hypothyroidism; E, euthyroidism.