Table 1.
Matched patient group | Other LTx patients | |||
---|---|---|---|---|
BOS | Non-BOS | BOS | Non-BOS | |
Total number | 7 | 7 | 3 | 40 |
BOS grade | ||||
I | 0 | n.a. | 0 | n.a. |
II | 3 | n.a. | 0 | n.a. |
III | 4 | n.a. | 3 | n.a. |
Mean follow-up | 38(69–9) | 39(65–32) | 21(17–33) | 17(76–6) |
Mean age | 51(24–61) | 50(22–61) | 39(23–58) | 41(17–64) |
Primary disease | ||||
CF | 1(14%) | 1(14%) | 2(67%) | 16(40%) |
Emphysema | 4(57%) | 4(57%) | 0(0%) | 14(35%) |
Fibrotic disease | 2(29%) | 2(29%) | 1(33%) | 10(25%) |
Infections | ||||
CMV | 0(0%) | 1(14%) | 0(0%) | 2(5%) |
EBV | 0(0%) | 0(0%) | 0(0%) | 1(2·5%) |
Pseudomonas | 3(42%) | 1(14%) | 2(67%) | 18(45%) |
Characteristics of 14 matched patients for longitudinal study, and the 43 other lung transplant (LTx) patients included in this study. A division is made between the patients who developed bronchiolitis obliterans syndrome (BOS) and the patients who have not developed BOS. Three patients had a cytomegalovirus (CMV) infection; two patients were CMV-negative and received lungs from a CMV-positive donor, one CMV-positive patient received lungs from a CMV-negative donor. One patient had an Epstein–Barr virus (EBV) reactivation. CF, cystic fibrosis; n.a., not available.