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. 2009 Jan 9;4(1):e4159. doi: 10.1371/journal.pone.0004159

Figure 6. Validation of Pax6-binding to Cspg2, Mab21l2, Olfm3, Spag5, and Tgfb2 loci by qChIP.

Figure 6

A) Confirmation of Pax6-binding in the promoter and 5 kb distal region of Cspg2/Vcan locus in lens chromatin. B) Confirmation of Pax6-binding in three regions (both 5′ and 3′ of the start site of transcription) of Mab21l2 locus in lens chromatin. C) Confirmation of Pax6-binding in the promoter of Olfm3 locus in lens chromatin. D) Confirmation of Pax6-binding in the promoter of Spag5 locus in lens chromatin. E) Confirmation of Pax6-binding in the promoter and 5 kb distal region of Tgfb2 locus in lens chromatin. The relative enrichments are shown as 1% of the input. The “peak” regions (A, B and C) and no-signal regions (NSR) are shown in Supporting Information.