Table 3.

Features of the insulinoma and glucagonoma syndromes

Data are from9,47,80-82,76,300-303

Features of the insulinoma syndrome

Neuroglycopenia (90%)

Amnesia or coma (47%)

Confusion (80%)

Visual changes (59%)

Convulsions (17%)

Altered consciousness (38%)

Sympathetic overdrive (60-70%)

Weakness (56%)

Sweating (69%)

Tremors (24%)

Palpitations (12%)

Hyperphagia (14%)

Obesity (<50%)

Features of the glucagonoma syndrome

Migratory necrolytic erythema (70- 90%)

Weight loss (80%)

Glucose intolerance (40-90%)

Normochromic, normocytic anemia (35-90%)

Hypoaminoacidemia (80%)

Diarrhea (25%)

Thromoboembolism (15-25%)

Glossitis, chelitis (15-40%)

Psychiatric symptoms (0-17%)