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. Author manuscript; available in PMC: 2008 Dec 31.
Published in final edited form as: Arch Immunol Ther Exp (Warsz). 2007 Mar 9;55(2):61–75. doi: 10.1007/s00005-007-0009-7

Figure 2. Molecular structure of ROCK1 and ROCK2.

Figure 2

ROCK sequences comprise a serine/threonine kinase domain located at the amino terminus of the protein, followed by a central coiled-coil domain containing the Rho-binding domain (RBD), and a carboxyl terminal pleckstrin homology (PH) domain with an internal cysteine-rich (CR) domain.