. Author manuscript; available in PMC: 2009 Oct 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 12;874(1-2):84–88. doi: 10.1016/j.jchromb.2008.09.007

Table 3.

Assessment of stability in plasma^a

Condition	Sunitinib
Condition	0.6 ng/mL	400 ng/mL
Freeze-thaw stability (−70°C)^b
Cycle 1	100.8	99.5
Cycle 2	99.6	93.3
Cycle 3	103.3	^c
Cycle 4	104.3	90.1
Short-term stability (room temperature)^b
Time = 1.0 h	100.0	99.58
Time = 2.0 h	89.39	106.68
Time = 4.0 h	87.91	111.21
Time = 6.0 h	96.3	94.14
Long-term stability (−70°C)^b
Time = 164 days	91.4	91.4

Expressed as the mean percentage change from time zero (nominal concentration).

Performed in triplicate.

Not done.