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GFP expression following Ad35-based vector results in longer transgene levels. The anterior segment of whole mouse eyes was examined for GFP expression following a single IVT injection of 1×109 pu of either Ad5.Null, Ad5.GFP (±HI-RGD), or Ad35.GFP (±HI-RGD). Naïve mice served as negative controls. Data are shown as GFP expression on Days 1, 7, 14, and 28 post IVT injection. Data are representative photographs of 1 mouse from each treatment group (n=15 mice/treatment group).
