Figure 7.

Combinations of MO to the different meltrins result in a reduction of CNC migration. (A) Embryos were injected at the 16-cell stage in D1-2 with the MO (0.33 ng each) and GFP as a lineage tracer to test their ability to prevent CNC migration. (B) Lateral views of representative embryos at tailbud stage. Migration was determined by the presence of GFP-labeled cells in the CNC pathways as evident in the GFP control. (C) Histogram representing the percentage of migration in embryos injected with the various MO (0.5 ng of each A9, A13, and A19) with or without the EC1-3 mRNA.