Table 3.
Pre-treatment genitourinary morbidity and genitourinary acute and late toxicity
| Pre-Tx | Acute† | Late‡ | Last late§ | ||
| Toxicity | Grade | n (%) | n (%) | n (%) | n (%) |
| Dysuria | 0 | 36 (92) | 20 (51) | 35 (90) | 38 (97) |
| 1 | 3 (8) | 13 (33) | 4 (10) | 1 (3) | |
| 2 | 0 | 5 (13) | 0 | 0 | |
| 3 | 0 | 1 (3) | 0 | 0 | |
| Incontinence | 0 | 34 (87) | 33 (84) | 34 (87) | 37 (94) |
| 1 | 4 (10) | 5 (13) | 4 (10) | 1 (3) | |
| 2 | 1 (3) | 1 (3) | 1 (3) | 1 (3) | |
| Retention | 0 | 20 (51) | 16 (41) | 23 (59) | 34 (86) |
| 1 | 13 (33) | 9 (23) | 11 (28) | 3 (8) | |
| 2 | 5 (13) | 12 (31) | 4 (10) | 1 (3) | |
| 3 | 1 (3) | 2 (5) | 1 (3) | 1 (3) | |
| Frequency/urgency | 0 | 23 (59) | 6 (15) | 17 (44) | 23 (59) |
| 1 | 13 (33) | 16 (41) | 15 (38) | 14 (36) | |
| 2 | 2 (5) | 15 (39) | 7 (18) | 2 (5) | |
| 3 | 1 (3) | 2 (5) | 0 | 0 | |
| Hematuria | 0 | 39 (100) | 39 (100) | 36 (92) | 37 (95) |
| 1 | 0 | 0 | 1 (3) | 2 (5) | |
| 2 | 0 | 0 | 2 (5) | 0 | |
| Highest GU* | 0 | 15 (39) | 1 (3) | 11 (28) | 19 (49) |
| 1 | 14 (36) | 13 (33) | 16 (41) | 13 (33) | |
| 2 | 8 (20) | 22 (56) | 11 (28) | 6 (15) | |
| 3 | 2 (5) | 3 (8) | 1 (3) | 1 (3) | |
Abbreviations: Pre-Tx = pre-treatment; * The highest toxicity in a patient was counted as a single event; † During therapy and until 3 months after completion; ‡ maximal late toxicity > 3 months after completion of therapy; § Incidence of late toxicity at last follow-up visit