Table 1.
Low bacterial dose
|
High bacterial dose
|
|||||
---|---|---|---|---|---|---|
IABC
|
No Pump
|
IABC
|
No Pump
|
p-value* | p-value+ | |
Mean Arterial Pressure (mmHg) | 88(5) | 86(3) | 89(2) | 89(2) | 0.44 | 0.66 |
Pulmonary Artery Occlusion Pressure (mmHg) | 7.2(0.4) | 7.0(0.5) | 7.0(0.6) | 8.3(0.6) | 0.07 | 0.65 |
PaO2 (mmHg, FiO2 = 25%) | 146(7) | 141(4) | 105(15) | 124(15) | 0.0006 | 0.75 |
Cardiac Index (l/min/kg) | 0.17(0.04) | 0.15(0.02) | 0.13(0.01) | 0.17(0.02) | 0.37 | 0.52 |
Ejection Fraction (%) | 56(4) | 57(2) | 56(2) | 55(2) | 0.83 | 0.94 |
Alanine Transferase (U/l) | 36.5(3.3) | 40.6(3.5) | 43.8(7.4) | 42.1(6.1) | 0.39 | 0.99 |
Lactic Dehydrogenase (U/l) | 53(8) | 70(10) | 65(13) | 39(5) | 0.19 | 0.77 |
Creatinine (mg/dl) | 0.63(0.05) | 0.67(0.03) | 0.5(0.03) | 0.57(0.04) | 0.002 | 0.50 |
Blood Urine Nitrogen (mg/dl) | 10.8(1.0) | 9.6(0.6) | 9.4(0.7) | 10.6(1.6) | 0.79 | 0.99 |
pH | 7.43(0.04) | 7.40(1.71) | 7.36(0.02) | 7.35(0.03) | 0.02 | 0.54 |
Lactate (mmol/l) | 2.4(1.0) | 1.6(0.2) | 0.74(0.1) | 1.53(0.4) | 0.09 | 0.08 |
SVRI (dyne* s-1cm-5kg-1) | 3.6(0.8) | 3.8(0.4) | 5.3(0.6) | 3.6(0.4) | 0.35 | 0.49 |
Plateau Pressure (cmH20) | 12.7(0.4) | 12.8(0.7) | 14.2(0.7) | 14.4(0.6) | 0.02 | 0.99 |
SvO2 (%) | 46.4(3.1) | 46.0(1.7) | 35.6(3.7) | 46.7(6.2) | 0.13 | 0.11 |
Central Venous Pressure (mmHg) | 4.3(0.7) | 4.3(0.5) | 6.5(1.5) | 4.6(0.0) | 0.18 | 0.31 |
n = | 6 | 12 | 8 | 7 |
, low versus high bacterial dose;
, Interaction IABC versus no pump