. Author manuscript; available in PMC: 2009 Jan 1.

Published in final edited form as: Ann Surg Oncol. 2008 Sep 19;15(12):3609–3613. doi: 10.1245/s10434-008-0141-6

Table 2.

Overall Diagnostic Performance of MRI

	True Negative	True Positive	False Negative	False Positive	Sensitivity	Specificity	MR accuracy

Inflammatory Cancer (N=24)	11/24 (46%)	7/24 (29%)	5/24 (21%)	1/24 (4%)	7/12 (58%)	11/12 (92%)	11/16 (69%)
HER-2 positive (N=15)	7/15 (46%)	4/15 (27%)	3/15 (20%)	1/15 (7%)	4/7 (57%)	7/8 (88%)	7/10 (70%)
HER-2 negative (N=9)	4/9 (45%)	3/9 (33%)	2/9 (22%)	0/9 (0%)	3/5 (60%)	4/4 (100%)	4/6 (67%)

The diagnostic accuracy of MRI for pCR was defined as the ratio between (true negative) / (true negative + false negative), which was not different between HER-2 positive and HER-2 negative patients.

Sensitivity, defined as the ratio between (true positive) / (true positive + false negative), and specificity, defined as the ratio between (true negative) / (true negative + false positive), also did not show significant differences between both groups of HER-2 patients.