Table 2.
Toxicity of the combination therapy with thalidomide and dexamethasone
| n/N | % | 95% CI | |
|---|---|---|---|
| Constipation | 140/379 | 37 | 32–42 |
| Thromboembolic event | 15/308 | 5 | 3–8 |
| Somnolence | 93/352 | 26 | 22–31 |
| Neuropathy | 101/373 | 27 | 23–32 |
| Depression | 27/265 | 10 | 7–14 |
| Discontinuation because of adverse event | 40/297 | 13 | 10–18 |
n, events; N, total number of patients for which the incidence of this adverse effect was reported.