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. Author manuscript; available in PMC: 2009 Jan 2.
Published in final edited form as: Annu Rev Phytopathol. 2008;46:101–122. doi: 10.1146/annurev.phyto.121107.104959

Figure 7.

Figure 7

A model of COR action in the plant cell (possibly all cell types). COR (structure shown) is secreted by Pst DC3000 into the plant cell and increases the affinity of the COI1 protein (as part of the SCFCOI1-ubiquitin ligase complex; not shown here) toward JAZ repressor and possibly other host proteins (denoted by “X”). The SCFCOI1 complex catalyzes ubiquitination of JAZ and other host proteins, which are then degraded through the 26S proteasome (denoted as “26S”). JAZ proteins normally function as repressors by physically binding to transcriptional activators (such as MYC2) of jasmonate response genes. In the stomatal guard cell, PAMPs (e.g., flagellin and LPS) are perceived by cognate immune receptors (e.g., flagellin receptor FLS2). Perception of PAMPs triggers stomatal closure, which requires SA, ABA, and OST1 kinase. COR-mediated inhibition of PAMP-triggered stomatal closure and other innate immune responses could be mediated by JAZ and/or “X” proteins.