Table 2.
49 genes that were up-regulated in GALT-knockout cells at both time (T) = +2 hours (+2h) and time (T) =+24 hours (+24h) after galactose challenge.
| 0.09% Glucose+0.01% Galactose | 0.05% Glucose+0.05% Galactose | |||||
|---|---|---|---|---|---|---|
| T= +2h | T= +24h | T= +2h | T= +24h | |||
| Gene Symbol/ID | Gene name | Fold Change | Fold Change | Fold Change | Fold Change | |
| 1 | AF118081 | Homo sapiens PRO1900 mRNA, complete cds. [AF118081] | 2.2159 | 4.1903 | 2.2199 | 2.4788 |
| 2 | ATAD2 | Homo sapiens ATPase family, AAA domain containing 2 (ATAD2), mRNA [NM_014109] | 2.5860 | 2.1912 | 2.6624 | 2.9207 |
| 3 | BLM | Homo sapiens Bloom syndrome (BLM), mRNA [NM_000057] | 3.9977 | 3.0104 | 4.1334 | 3.0475 |
| 4 | BRCA1 | Homo sapiens breast cancer 1, early onset (BRCA1), transcript variant BRCA1b, mRNA [NM_007295] | 2.9278 | 2.7657 | 3.1038 | 2.7372 |
| 5 | BTBD11 | Homo sapiens BTB (POZ) domain containing 11 (BTBD11), transcript variant 1, mRNA [NM_152322] | 4.6453 | 3.6777 | 3.8577 | 2.9645 |
| 6 | C14orf145 | Homo sapiens chromosome 14 open reading frame 145 (C14orf145), mRNA [NM_152446] | 2.3419 | 2.3638 | 3.1662 | 2.6317 |
| 7 | C15orf42 | Homo sapiens chromosome 15 open reading frame 42, mRNA (cDNA clone IMAGE:3940845), partial cds. [BC002881] | 2.5754 | 2.6657 | 2.6642 | 2.5498 |
| 8 | C1orf135 | Homo sapiens chromosome 1 open reading frame 135 (C1orf135), mRNA [NM_024037] | 6.0206 | 2.4856 | 4.5836 | 2.1706 |
| 9 | C6orf167 | Homo sapiens chromosome 6 open reading frame 167 (C6orf167), mRNA [NM_198468] | 2.5044 | 2.1085 | 2.9092 | 2.6598 |
| 10 | CALB2 | Homo sapiens calbindin 2, 29kDa (calretinin) (CALB2), transcript variant CALB2, mRNA [NM_001740] | 4.6864 | 3.5229 | 5.6453 | 2.1511 |
| 11 | CENPO | Homo sapiens centromere protein O (CENPO), mRNA [NM_024322] | 3.5715 | 2.6316 | 3.0162 | 2.2971 |
| 12 | CHAF1B | Homo sapiens chromatin assembly factor 1, subunit B (p60) (CHAF1B), mRNA [NM_005441] | 2.7261 | 2.1368 | 2.0194 | 2.2379 |
| 13 | CKAP2L | Homo sapiens cytoskeleton associated protein 2-like (CKAP2L), mRNA [NM_152515] | 2.2616 | 3.9039 | 2.7397 | 3.2746 |
| 14 | COMP | Homo sapiens cartilage oligomeric matrix protein (COMP), mRNA [NM_000095] | 5.2865 | 3.3143 | 3.2940 | 3.0677 |
| 15 | DIRAS3 | Homo sapiens DIRAS family, GTP-binding RAS-like 3 (DIRAS3), mRNA [NM_004675] | 6.7295 | 10.6971 | 7.9285 | 11.6346 |
| 16 | DKFZP564O0523 | Homo sapiens hypothetical protein DKFZp564O0523 (DKFZP564O0523), mRNA [NM_032120] | 2.3763 | 3.9786 | 2.0353 | 3.4618 |
| 17 | DLX2 | Homo sapiens distal-less homeobox 2 (DLX2), mRNA [NM_004405] | 3.4586 | 2.6290 | 2.8188 | 2.2133 |
| 18 | DTL | Homo sapiens denticleless homolog (Drosophila) (DTL), mRNA [NM_016448] | 4.0266 | 2.0709 | 3.3927 | 2.4674 |
| 19 | ENST00000272831 | Homo sapiens cDNA FLJ39660 fis, clone SMINT2006801. [AK096979] | 3.2824 | 3.3055 | 3.3231 | 2.8630 |
| 20 | EXO1 | Homo sapiens exonuclease 1 (EXO1), transcript variant 3, mRNA [NM_003686] | 3.8826 | 2.7400 | 3.3765 | 2.6737 |
| 21 | FANCA | Homo sapiens Fanconi anemia, complementation group A (FANCA), transcript variant 1, mRNA [NM_000135] | 4.4405 | 2.5373 | 3.9381 | 2.0839 |
| 22 | FANCD2 | Homo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 2, mRNA [NM_001018115] | 2.3172 | 2.7902 | 2.7712 | 2.3316 |
| 23 | FEN1 | Homo sapiens flap structure-specific endonuclease 1 (FEN1), mRNA [NM_004111] | 4.6554 | 2.0057 | 2.9660 | 2.0220 |
| 24 | FLJ25416 | Homo sapiens hypothetical protein FLJ25416 (FLJ25416), mRNA [NM_145018] | 3.3113 | 2.4363 | 4.5802 | 2.9110 |
| 25 | FLJ39660 | Homo sapiens mRNA; cDNA DKFZp434P055 (from clone DKFZp434P055). [AL834537] | 2.7470 | 3.6942 | 2.4951 | 2.8696 |
| 26 | FOXF1 | Homo sapiens forkhead box F1 (FOXF1), mRNA [NM_001451] | 3.8644 | 2.3633 | 3.0667 | 2.0672 |
| 27 | GRB14 | Homo sapiens growth factor receptor-bound protein 14 (GRB14), mRNA [NM_004490] | 11.6293 | 4.3499 | 4.9834 | 3.5137 |
| 28 | GSG2 | Homo sapiens cDNA FLJ32129 fis, clone PEBLM2000213, weakly similar to Mus musculus genes for integrin aM290, hapsin. [AK056691] | 4.0174 | 3.0022 | 3.6721 | 2.4851 |
| 29 | HIST1H4B | Homo sapiens histone 1, H4b (HIST1H4B), mRNA [NM_003544] | 6.0164 | 2.5334 | 4.5282 | 2.5567 |
| 30 | HIST1H4L | Homo sapiens histone 1, H4l (HIST1H4L), mRNA [NM_003546] | 4.9153 | 2.2718 | 4.6618 | 2.4205 |
| 31 | IL8 | Homo sapiens interleukin 8 (IL8), mRNA [NM_000584] | 13.2970 | 3.7871 | 40.6700 | 6.9918 |
| 32 | KIAA1794 | Homo sapiens KIAA1794 (KIAA1794), mRNA [NM_018193] | 2.3180 | 2.2701 | 2.5657 | 2.3368 |
| 33 | KRTAP2-4 | Homo sapiens keratin associated protein 2–4, mRNA (cDNA clone MGC:74790 IMAGE:3907481), complete cds. [BC063625] | 14.5565 | 2.1635 | 8.8681 | 2.2416 |
| 34 | LCP1 | Homo sapiens lymphocyte cytosolic protein 1 (L- plastin) (LCP1), mRNA [NM_002298] | 5.3567 | 3.1974 | 6.5640 | 3.5841 |
| 35 | LIN9 | Homo sapiens lin-9 homolog (C. elegans) (LIN9), mRNA [NM_173083] | 2.0351 | 2.2094 | 2.8722 | 2.5001 |
| 36 | MALL | Homo sapiens mal, T-cell differentiation protein- like (MALL), mRNA [NM_005434] | 3.7111 | 2.1212 | 2.2459 | 2.1592 |
| 37 | MCM8 | Homo sapiens MCM8 minichromosome maintenance deficient 8 (S. cerevisiae) (MCM8), transcript variant 2, mRNA [NM_182802] | 2.4416 | 2.0233 | 2.7290 | 2.1927 |
| 38 | NCF2 | Homo sapiens neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) (NCF2), mRNA [NM_000433] | 4.0104 | 2.3476 | 5.5209 | 2.4254 |
| 39 | PODXL | Homo sapiens podocalyxin-like (PODXL), transcript variant 2, mRNA [NM_005397] | 6.1891 | 3.7635 | 6.9373 | 3.4990 |
| 40 | RBL1 | Homo sapiens retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, mRNA [NM_002895] | 3.1106 | 2.5367 | 3.3424 | 6.0484 |
| 41 | RGS20 | Homo sapiens regulator of G-protein signalling 20 (RGS20), transcript variant 1, mRNA [NM_170587] | 3.2261 | 3.2284 | 3.1573 | 2.8231 |
| 42 | RRM2 | Homo sapiens ribonucleotide reductase M2 polypeptide (RRM2), mRNA [NM_001034] | 4.2204 | 2.3773 | 3.7226 | 3.0227 |
| 43 | SHCBP1 | Homo sapiens SHC SH2-domain binding protein 1 (SHCBP1), mRNA [NM_024745] | 2.0100 | 2.3920 | 2.6868 | 2.7386 |
| 44 | VRK1 | Homo sapiens vaccinia related kinase 1 (VRK1), mRNA [NM_003384] | 2.8160 | 2.1657 | 2.6390 | 2.0119 |
| 45 | WDHD1 | Homo sapiens WD repeat and HMG-box DNA binding protein 1 (WDHD1), transcript variant 1, mRNA [NM_007086] | 2.8091 | 2.2974 | 3.0100 | 2.6967 |
| 46 | XRCC2 | Homo sapiens mRNA; cDNA DKFZp781P0919 (from clone DKFZp781P0919). [CR749256] | 4.9724 | 2.4844 | 2.7891 | 2.8756 |
| 47 | ZNF141 | Homo sapiens zinc finger protein 141 (ZNF141), mRNA [NM_003441] | 7.7618 | 16.5265 | 5.5300 | 12.2949 |
| 48 | ZNF223 | Homo sapiens zinc finger protein 223 (ZNF223), mRNA [NM_013361] | 3.0949 | 8.0183 | 6.0460 | 19.5330 |
| 49 | ZWINT | Homo sapiens ZW10 interactor (ZWINT), transcript variant 4, mRNA [NM_001005414] | 2.2286 | 2.1947 | 2.5364 | 2.4322 |