Table 1.
Bias of Estimates and Coverage Probabilities of Wald-Based 95% Confidence Intervals for SCE(t) With t = 24 Months
| Bias
|
Coverage probability
|
||||
|---|---|---|---|---|---|
| VE | β | Mean | Median | Bootstrap | Analytic |
| ~.3 | .1 | −.002 | 0 | .946 | .948 |
| .2 | −.007 | −.007 | .943 | .949 | |
| 1 | −.006 | −.003 | .943 | .946 | |
| ∞ | −.007 | .005 | .948 | .953 | |
| ~.6 | .1 | .003 | .006 | .939 | .940 |
| .2 | .013 | .015 | .945 | .945 | |
| 1 | .042 | .020 | .933 | .912 | |
| ∞ | .035 | 0 | .935 | ||
NOTE: Analytic coverage probabilities when VE ≈ .6, β = ∞ are not given, because in many simulations there were no failures in the vaccine arm.