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. Author manuscript; available in PMC: 2009 Jan 2.
Published in final edited form as: J Am Stat Assoc. 2007 Jun;102(478):573–582. doi: 10.1198/016214507000000130

Table 1.

Bias of Estimates and Coverage Probabilities of Wald-Based 95% Confidence Intervals for SCE(t) With t = 24 Months

Bias
Coverage probability
VE β Mean Median Bootstrap Analytic
~.3 .1 −.002 0 .946 .948
.2 −.007 −.007 .943 .949
1 −.006 −.003 .943 .946
−.007 .005 .948 .953
~.6 .1 .003 .006 .939 .940
.2 .013 .015 .945 .945
1 .042 .020 .933 .912
.035 0 .935

NOTE: Analytic coverage probabilities when VE ≈ .6, β = ∞ are not given, because in many simulations there were no failures in the vaccine arm.