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. Author manuscript; available in PMC: 2009 Jan 2.
Published in final edited form as: Curr Immunol Rev. 2007 Aug;3(3):151–159. doi: 10.2174/157339507781483496

Fig. 3. Endogenous natural Treg in neonates are competent to downregulate both Th1 and Th2 responses by neonatal CD4+ cells.

Fig. 3

CD4+ lymph nodes from 7 day neonatal BALB/c mice were treated with anti-CD25 plus complement or with complement alone (control cells). Both the control and the specifically treated cells were then incubated with anti-CD3 plus anti-CD28 for 48 hr and the cytokine content of the supernatants was tested in specific ELISA.