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. 2009 Jan 23;5(1):e1000267. doi: 10.1371/journal.pcbi.1000267

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Engelen et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Allophycocyanin structure (PDB file 1all:B). Top: residues are colored from blue (strong signal) to red (low signal) passing through white by conservation (A) and by physical-chemical properties (B), with inaccessible residues in red. The experimental interaction site is blue in (C). Bottom: cluster seeds computed based on conservation (D) and based on physical-chemical properties (E) are colored from blue to white accordingly to and values respectively. Prediction (F) is computed by extending both seeds in (D) and (E); colors map mixed trace values.

Inline graphic — Allophycocyanin structure (PDB file 1all:B). Top: residues are colored from blue (strong signal) to red (low signal) passing through white by conservation (A) and by physical-chemical properties (B), with inaccessible residues in red. The experimental interaction site is blue in (C). Bottom: cluster seeds computed based on conservation (D) and based on physical-chemical properties (E) are colored from blue to white accordingly to and values respectively. Prediction (F) is computed by extending both seeds in (D) and (E); colors map mixed trace values.