Table 4. Effect size of LPL variants on TG levels.

SNP	Position	f_afr	f_eur	f_all	p_trg_all	p_int_trg	p_trg_afr	effect_all±se	effect_afr±se	effect_eur±se
rs10096633	19875201	0.50	0.82	0.57	2.7E-06	0.15	7.1E-03	6.2±1.2	4.5±1.6	6.6±3.1
rs1011685	19875049	0.95	0.87	0.93	2.0E-05	0.027	0.25	11.5±2.5	4.4±3.6	21.5±4.5
rs325	19863608	0.94	0.86	0.93	4.5E-05	0.033	0.23	10.3±2.4	4.3±3.4	19.3±4.4
rs17482753	19876926	0.95	0.85	0.94	4.9E-05	0.023	0.33	10.8±2.5	3.7±3.6	21.4±4.5
rs328	19864004	0.94	0.86	0.93	7.1E-05	0.050	0.22	10.2±2.4	4.5±3.4	18.6±4.5
rs12679834	19864713	0.92	0.86	0.91	2.7E-04	0.013	0.33	8.3±2.1	3.1±3.0	17.8±4.3
rs327	19863816	0.55	0.68	0.59	7.8E-04	0.86	8.3E-03	4.3±1.2	4.4±1.6	3.7±2.8
rs1569209	19874450	1.00	0.90	0.98	9.9E-04	0.86	0.62	16.6±4.7	17.3±32.5	18.9±5.6
rs13702	19868772	0.43	0.66	0.48	1.1E-03	0.81	0.042	4.1±1.2	3.4±1.6	2.2±2.8
rs3779788	19847373	0.98	0.91	0.95	1.2E-03	0.60	0.14	10.4±3.0	8.6±5.4	9.3±4.5
rs343	19855067	0.95	0.94	0.95	1.3E-03	0.27	0.16	9.2±2.7	5.7±3.8	12.9±5.3
rs1059611	19868843	0.79	0.83	0.81	2.1E-03	0.23	0.11	4.9±1.5	3.3±1.9	8.2±3.5
rs295	19860518	0.57	0.73	0.61	3.4E-03	0.61	8.8E-03	3.9±1.3	4.5±1.6	1.6±2.9
rs3916027	19869148	0.55	0.69	0.58	4.6E-03	0.77	0.025	3.6±1.2	3.8±1.6	2.2±2.8
rs264	19857460	0.87	0.87	0.86	5.3E-03	0.23	0.089	5.1±1.7	4.2±2.3	9.2±3.9
rs7000460	19848082	0.74	1.00	0.78	5.5E-03	0.69	0.051	4.4±1.5	3.7±1.8	0.12±4.39
rs17091872	19876257	0.81	0.84	0.81	5.7E-03	0.27	0.25	4.4±1.5	2.4±2.0	4.6±3.5
rs15285	19868947	0.43	0.67	0.48	5.9E-03	0.70	0.047	3.5±1.2	3.3±1.6	0.30±2.72
rs3289	19867472	0.92	1.00	0.92	8.1E-03	0.23	0.22	7.0±2.5	3.8±3.0	10.3±7.5
rs263	19857092	0.61	0.86	0.64	8.3E-03	0.092	0.12	3.5±1.3	2.6±1.7	5.6±3.1
rs2197089	19870653	0.15	0.41	0.21	9.3E-03	0.72	0.027	4.1±1.5	5.1±2.2	1.3±2.8

P-values for association of TRG with genotype in the total population (p_trg_all) and JHS-AFR-2_LPL (p_trg_afr); SNPs with p<0.0006 are shown in bold. The p-value for interaction (p_int_trg) is for the significance of the genotype×local ancestry term in the linear regression model for the total population (p<0.05 is shown in bold). The percent change in TG level per LPL allele is shown with standard error for the total population (effect_all), JHS-AFR-2_LPL (effect_afr) and JHS-EUR-1_2_LPL (effect_eur). The SNP frequencies in the total population (f_all), JHS-AFR-2_LPL (f_afr) and JHS-EUR-2_LPL (f_eur) are also shown, as well as the chromosomal position in bases on chromosome 8.