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. 2009 Jan 13;4(1):e4183. doi: 10.1371/journal.pone.0004183

Figure 10. Elevated α-secretase activity in the brain of h-S100A7 transgenic mice.

Figure 10

In this study, h-S100A7 transgenic mice were identified by dot blot hybridization of tail skin DNA samples with labeled h-S100A7 cDNA (for the h-S100A7 transgene). Expression of serum S100A7 (A) content in 1-month old h-S100A7 and age-, gender-, and stain-matched WT control mice was assessed by western blot analysis. The brains of h-S100A7 transgenic mice and WT control mice were assessed for α-secretase activity (B) using an activity assay kit (R&D Systems). Values represent mean±SEM and are expressed as percent of WT control mice group. *P<0.05, two-tailed Student t-test; n = 4 per group.