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. 2009 Jan 9;284(2):862–871. doi: 10.1074/jbc.M804632200

FIGURE 4.

FIGURE 4.

Streptolysin O mediates apoptosis of human phagocytic cells. SLO expression in GAS is responsible for the induction of apoptosis in the human monocytic cell line THP1 (A) and in freshly isolated PBMCs from human blood (B). C, SLO is also necessary (in GAS) and sufficient (in L. lactis) for induction of neutrophil apoptosis. LL, L. lactis.