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Dissociation constants (Kd) for the interaction of E3, (β-15-66)2, and (Bβ-1-66)2 with LS174T CD44 and HL60 CD44s obtained by SPR
Fibrinogen fragments were injected at different concentrations, and their association with immobilized LS174T CD44 and HL60 CD44s was monitored by the change in the SPR response. NB indicates no binding was detected at up to 10 μm of E3.
|
Dissociation constants (Kd)
|
|||
|---|---|---|---|
| E3 | (β15-66)2 | (Bβ1-66)2 | |
| nm | μm | ||
| CD44 | NB | 97 | 1.8 |
| CD44s | NB | 243 | 3.1 |
