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. 2009 Jan 9;284(2):848–854. doi: 10.1074/jbc.M808045200

FIGURE 3.

FIGURE 3.

Effect of Spry2 overexpression on the activation of Akt, HDM2, and p53. A and B, a vector control cell strain, MSU1.1-VC, and a cell strain overexpressing Spry2, MSU1.1-S62, were treated with EGF and analyzed as in Fig. 2, A and B. pp85, phospho-85; pAkt, phospho-Akt; pHDM2, phospho-HDM2. C and D, the indicated cell strains were exposed to UV radiation as above and analyzed as in Fig. 2, C and D.