Figure 6.

Core circadian oscillator gene expression is asynchronous in Mc3r−/− mice compared with WT mice. Double plotted gene expression data for (A) Arntl/Bmal1 (B) Naps2 and (C) Per2 under AL (left panels, gray squares represents lights off) or RF conditions (right panels, feeding time is indicated by a dark gray rectangle). Lights off phase is indicated by a light gray shade. Significant differences (*) in gene expression were observed between Mc3r−/− mice compared with WT at each time point (p < 0.05) (n = 4–5 per group).