Figure 6.

Alignment of the CCT domains from different plant species. A, WebLogo representation of consensus sequence from CCT domains from rice and Arabidopsis CO-like proteins (Griffiths et al., 2003; Yan et al., 2004b) and nonmutant ZCCT1 and ZCCT2 proteins. The sizes of the different letters are proportional to the frequency of the amino acid in the multiple sequence alignment. B, Alignment of the CCT domains from wheat and Aegilops ZCCT1 and ZCCT2 proteins. Arrows point to natural mutations discovered in conserved amino acids that may affect protein function. Ae. spelt., Ae. speltoides; T.m., T. monococcum. C, Conserved amino acids between CCT and HAP2. Subdomains NF-YA1 (interacts with HAP3 and HAP5) and NF-YA2 (interacts with CCAAT DNA sequences) are indicated below.