Table 2.

A-CGH analysis of bone marrow from MDS patients.

			CGH results
	#	Cytogenetics	Gain	Loss	# changes
Abnormal Metaphase Cytogenetics	1	45,XY,t(1;4)(q32;q35),del(5) (q13q33), del(8)(p11.2-21)[20]	17p12, 22q11, 22q13	5q21	4
	3	46,XY,del(20)(q11.2q13.3)[19]/46,XY[1]	2p22.3	3p14.1	2
	10	47,XX,+21[20]	1p36.32	NCD	1
	12	46–47,XY,add(3)(q11.2),del(5) (q13q33),+8,-15,-16,+1-2 mar[cp20]	3q13-3q25, 4q, 15q12-15q21, 16q12-qter	4p, 8	ND
	14	46,XX,del(20)(q11.2q13.3)[7]/46,XX[13]	2q22-q23, 21q22.3,	20q	3
	15	46,XY,del(7)(q22q34)[4]/45,X,-Y[2]	NCD	7q21.1-31.3	21
	18	48-49,XY,+8,+9,+11[cp6]/46,XY[17]	9p13.3, 11p12, 17q24	4q21.2	4
	23	47,XY,+Y[3]/47,XY,+8[3]/46,XY[16]	NCD	2p14, 2q14.2, 2q23, 4p16.1, 4p15.1, 6p21.2, 6q12, 6q16.1, 6q23, 13q22.3, 15q21.1, 16p13.2	12
	26	46, XX,der(16)t(1;16) (q12;q11.2)[17]/46,XX[3]	1p36, 1q arm, 22q13.33	8q24, 10q26; 16q arm	83
	27	46,XY,del(5)(q15q31)[11]/46,XY[9]	NCD	13q21.1, Xq27.3	2
	28	45,XX,-7[20]	1p36.32, 1q31, 6q24	whole 7, 8q24.2	49
	29	46,XY, del (5) (q22q33) [20]	2p21	5q32	4
	32	47,XY,+Y[20]	Xq23, Yq11.2	8q24.2	4
	33	46,XY,del(20)(q11.2)[6]/46, idem,del(7)(p12)[2]/46,XY,ider(20) (q10)del(20)(q11.2)[8]/46,XY[4]	20q13.33	12p13.2, 15q21.3, 20p11-13, 20q11-13	20
	34	47,XY,+11[2]/46,XY[18]	1p36.3, 10q26.3, 10q13.33, 22q13.3	3q22	5
	36	47,XX,der (3) (3pter-3q13.1::3q21-3q21::3q24-3qter),+8[22]	NCD	3q13, 3q21.3	6
	37	46,XY,del(7)(q11.2)[10]/46,XY,add(12)(q24.3)[7]/46,XY[3]	NCD	11q14	1
	9	45,X,-X[5]/46,XX[15]	NCD	NCD	0
	11	48,XY,+8,+8[6]/46,XY[14]	NCD	NCD	0
Normal Metaphase Cytogenetics	2	46,XY[20]	2q tel, 3p21.3, 5q33, 7p12, 7q11.23, 11ptel, 11p15.5, 17p12, 17q21, 22q11.2, 22q13.1	1q44, 2q23, 3p14, 3q26, 21q11.2, Xq12	20
	7	46,XX[20]	NCD	9q21.11	1
	13	46,XY[20]	1p36.13, 1q22, 2p24, 3p22-3p25.3, 4p15.2, 4q32, 5q32, 6p21.1, 6q21, 14q12, 17p13.3, 17q24	NCD	15
	16	46,XX[20]	NCD	1p21-1p22.1 (contiguous)	2
	17	46,XY[20]	1pter, 1p36.33, 2q35, 2q37.3, 4p, 5ptel, 6q24, 7ptel 8qtel, 9qtel, 10qtel, 13qtel, 17ptel, 17qtel, 19qtel 20qtel, 22qtel	NCD	23
	19	46,XY[20]	TNTL	TNTL	116
	20	46,XY[20]	3q26	12q21.3	2
	21	46,XY[20]	1p36.33, 9q34, 17p13.3	4q23, Xq21, Xq27.3, Xq28	8
	22	46,XY[20]	7q11.2, 8q23, 9q21.2, 14q23.1, Xq21.1	1p35.1, 2q22, 4q32, 7p21, 9q21, 11p12, 12q12, 13q22.3, 15q23, 21p21.3	15
	24	46,XY[20]	3p25, 5q32, 17p13.3	NCD	5
	25	46,XY[20]	2q37.1, 5p15.33, 18p11.32, 19p13.2, Xp22.33	NCD	5
	35	46,XX[20]	1q12	12q24.3	2
	38	46,XY	NCD	2q32.3, 3p26.3, 8p12	3
	39	46,XY[20]	10q26.3 (contiguous)	NCD	2
	8	46,XY[6]	NCD	NCD	0
	30	46,XY[20]	NCD	NCD	0
	31	46,XY[20]	NCD	NCD	0
	5	No growth	10q26.3	NCD	1
	4	No growth	NCD	NCD	0

Karyotype of patients as determined by traditional karyotyping and A-CGH are shown. NCD, no changes detected; ND, not determined; TNTL, too numerous to list.