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. Author manuscript; available in PMC: 2009 Jan 5.
Published in final edited form as: J Am Chem Soc. 2007 Sep 22;129(41):12404–12405. doi: 10.1021/ja075802+

Table 1.

Optimization of the arylation conditionsa

graphic file with name nihms-64156-t0002.jpg
Entry Base PhX Yield,
%
1 KOtBu PhF or PhOTs No arylation
2b KotBu PhCl 40
3 KotBu PhBr 51
4 KotBu PhI 61
5 LiOtBu PhCl, PhBr or PhOTs No arylation
6 LiOtBu PhI 93
a

Substrate (1 equiv), aryl halide (3 equiv), base (2 equiv). Yields are isolated yields.

b

PhCl (4 equiv), base (3 equiv).