Skip to main content
. Author manuscript; available in PMC: 2009 Jan 5.
Published in final edited form as: J Am Chem Soc. 2007 Sep 22;129(41):12404–12405. doi: 10.1021/ja075802+

Table 3.

Arylation scope with respect to heterocyclesa

graphic file with name nihms-64156-t0012.jpg
Entry Heterocycle Product Yield, %
1b graphic file with name nihms-64156-t0013.jpg graphic file with name nihms-64156-t0014.jpg 59
2c graphic file with name nihms-64156-t0015.jpg graphic file with name nihms-64156-t0016.jpg 59
3 graphic file with name nihms-64156-t0017.jpg graphic file with name nihms-64156-t0018.jpg 84
4 graphic file with name nihms-64156-t0019.jpg graphic file with name nihms-64156-t0020.jpg 82
5d graphic file with name nihms-64156-t0021.jpg graphic file with name nihms-64156-t0022.jpg 57
6e graphic file with name nihms-64156-t0023.jpg graphic file with name nihms-64156-t0024.jpg 89
7d graphic file with name nihms-64156-t0025.jpg graphic file with name nihms-64156-t0026.jpg 78
8 graphic file with name nihms-64156-t0027.jpg graphic file with name nihms-64156-t0028.jpg 70
a

Substrate (1 equiv), iodobenzene (3 equiv), base (2 equiv). Yields are isolated yields.

b

2,5-Diphenyloxazole also isolated (7%).

c

2-Phenylthiazole also isolated (37%).

d

KOtBu base.

e

LiOtBu/KOtBu base (1:1).