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. Author manuscript; available in PMC: 2009 Jan 5.
Published in final edited form as: Connect Tissue Res. 2004;45(1):50–59. doi: 10.1080/03008200490278142

Figure 3.

Figure 3

Effect of BMP-7 and noggin gene transfer on cementoblast-induced mineralization in polymer scaffolds at 3 weeks. Left panels display low power photomicrographs, whereas the right panels show high power images of OCCM cell-polymer implants treated by BMP-7 or noggin gene transfer. Mineral spicules were formed in all groups and were covered with spindle-like cells. However, implants retrieved from Ad-NOGΔB2–treated OCCM cells exhibited a paucity of mineral induction. There was vascularization among the mineral spicules; however, no bone marrow-like tissue was formed in any group (H&E staining; bar = 250 µm; n = 3 animals/group).