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. Author manuscript; available in PMC: 2009 Jan 5.
Published in final edited form as: Connect Tissue Res. 2004;45(1):50–59. doi: 10.1080/03008200490278142

Figure 5.

Figure 5

Histomorphometric analysis of mineralized tissue area and density of the PLGA-cell implants at 3 and 6 weeks following gene transfer. Histomorpho-metric analysis was performed to measure. (A) Mineralized area of implants at 3 and 6 weeks. Implants from Ad-NOGΔB2 treatment of OCCM cells resulted in a reduction in mineral area compared with NT and Ad-GFP groups (*p < .05, **p < .01), while Ad-BMP-7 treatment had no effect on the induction of mineral. (B) Mineral density of implants from each group at 3 and 6 weeks. The mineral density of Ad-NOGΔB2 treated specimens were greatly reduced at 3 weeks compared with NT and Ad-GFP groups (*p< .05,** p <.01), at 6 weeks, Ad-NOGΔB2 treatment demonstrated slightly reduced mineral density when compared with NT (**p < .01), although it was not different compared with the implants from Ad-BMP-7 or Ad-GFP gene transfer.