Table 5.
Cross-tabulation of patient characteristics and diagnoses of generalized anxiety and depression stratified by use of psychiatric medications
| No Psychiatric Medication Used
|
Psychiatric Medication Used
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Variable | n | GAD, DEP, GAD & DEP (n = 115) | NEITHER (n = 129) | p Value | n | GAD, DEP, GAD & DEP (n = 90) | NEITHER (n = 29) | p Value |
| Gender | ||||||||
| Male | 156 | 69 (44%) | 87 (56%) | 0.233 | 53 | 43 (81%) | 10 (19%) | 0.283 |
| Female | 88 | 46 (52%) | 42 (48%) | 66 | 47 (71%) | 19 (29%) | ||
| Marital status | ||||||||
| Single | 41 | 23 (56%) | 18 (44%) | 0.312 | 16 | 14 (88%) | 2 (12%) | 0.312 |
| Married | 187 | 85 (45%) | 102 (55%) | 89 | 63 (71%) | 26 (29%) | ||
| Divorced | 10 | 4 (40%) | 6 (60%) | 10 | 9 (90%) | 1 (10%) | ||
| Separated | 2 | 2 (100%) | 0 | 3 | 3 (100%) | 0 | ||
| Widowed | 4 | 1 (25%) | 3 (75%) | 1 | 1 (100%) | 0 | ||
| Education | ||||||||
| <High school | 8 | 5 (63%) | 3 (37%) | 0.259 | 3 | 3 (100%) | 0 | 0.664 |
| High school diploma | 32 | 16 (50%) | 16 (50%) | 18 | 14 (78%) | 4 (22%) | ||
| Some college | 56 | 32 (57%) | 24 (23%) | 37 | 28 (76%) | 9 (24%) | ||
| College degree | 101 | 45 (45%) | 56 (55%) | 43 | 30 (70%) | 13 (30%) | ||
| Graduate degree | 46 | 17 (37%) | 29 (63%) | 18 | 15 (83%) | 3 (17%) | ||
| Not recorded | 1 | 0 | 1 (100%) | 0 | 0 | 0 | ||
| Time from diagnosis | ||||||||
| <3 months | 11 | 6 (55%) | 5 (45%) | 0.771 | 6 | 5 (83%) | 1 (17%) | 0.528 |
| 3–12 months | 72 | 35 (49%) | 37 (51%) | 33 | 27 (82%) | 6 (18%) | ||
| 13–24 months | 66 | 33 (50%) | 33 (50%) | 32 | 25 (78%) | 7 (22%) | ||
| >24 months | 95 | 41 (43%) | 54 (57%) | 48 | 33 (69%) | 15 (31%) | ||
| WHO tumor grade | ||||||||
| I | 6 | 2 (33%) | 4 (67%) | 0.542 | 0 | 0 | 0 | 0.501 |
| II | 31 | 19 (61%) | 12 (39%) | 25 | 22 (85%) | 4 (15%) | ||
| III | 84 | 38 (45%) | 46 (55%) | 43 | 30 (71%) | 12 (29%) | ||
| IV | 114 | 50 (44%) | 64 (56%) | 48 | 35 (73%) | 13 (27%) | ||
| Not recorded | 3 | 3 (100%) | 0 | 1 | 1 (100%) | 0 | ||
| Brain not primarya | 6 | 3 (50%) | 3 (50%) | 2 | 2 (100%) | 0 | ||
| Tumor site | ||||||||
| Right hemisphere | 114 | 56 (49%) | 58 (51%) | 0.777 | 55 | 38 (68%) | 18 (35%) | 0.176 |
| Left hemisphere | 106 | 49 (46%) | 57 (54%) | 52 | 43 (83%) | 9 (17%) | ||
| Otherb | 24 | 10 (42%) | 14 (58%) | 12 | 9 (82%) | 2 (18%) | ||
| Past/current medical illnessc | ||||||||
| Yes | 53 | 29 (55%) | 24 (45%) | 0.211 | 43 | 34 (79%) | 9 (21%) | 0.511 |
| No | 191 | 86 (45%) | 105 (55%) | 76 | 56 (74%) | 20 (26%) | ||
| Recurrent diseased | ||||||||
| Yes | 55 | 23 (42%) | 32 (58%) | 0.443 | 34 | 27 (79%) | 7 (21%) | 0.641 |
| No | 189 | 92 (49%) | 97 (51%) | 85 | 63 (74%) | 22 (26%) | ||
| Ethnicity | ||||||||
| White | 220 | 110 (48%) | 120 (52%) | 0.151 | 115 | 86 (75%) | 29 (25%) | 0.571 |
| Nonwhite | 14 | 5 (36%) | 9 (64%) | 4 (100%) | 0 | |||
| Previous psychiatric illness | ||||||||
| No | 239 | 111 (46%) | 128 (54%) | 0.191 | 105 | 79 (75%) | 26 (25%) | 0.257 |
| Yes | 5 | 4 (80%) | 1 (20%) | 14 | 11 (79%) | 3 (21%) | ||
Abbreviations: GAD, generalized-anxiety-only group; DEP, depression-only group; GAD & DEP, generalized anxiety and depression group; NEITHER, did not meet criteria for generalized anxiety or depression.
Brain not primary indicates that brain cancer was not the primary diagnosis or that brain tumor was the result of metastasis.
Other included diagnoses such as bilateral tumor location.
Past/current medical illness included previous cardiac events, hypertension, diabetes mellitus, hyperlipidemia, hypercholesterolemia, significant renal disease requiring dialysis, history of psychiatric illness, and/or history of other cancers.
Recurrent disease indicates tumor growth >25% on MRI.