Table 5.

Multivariate analysis of significant prognostic factors

Variable	Contrast	Hazard Ratio (95% CI)	p-Value
Cerebral symptoms	Yes vs. no	0.4 (0.2,0.8)	0.011
LS imaging	Positive vs. negative	2.4 (1.1,5.5)	0.031
Cytology	Positive vs. negative	3.5 (1.3,9.8)	0.017
CSF glucose	>65 vs. ≤65 mg/dl	3.1 (1.3,7.7)	0.012

Abbreviations: CI, confidence interval; LS, lumbosacral; CSF, cerebrospinal fluid.

Because of a large number of comparisons (18) compared to the number of events (43), we could not fit all the covariates into a single stable model. Because several of the covariates had some missing values, we performed manual backward stepping starting with all the covariates in the model and omitting all covariates with p > 0.5.