Table 3.
Age- and drug-dependence of BS mutants in chronic drug exposure
Treatment | MRT (s) | ||
---|---|---|---|
1d | 2d | 3d | |
bss control | 63 ± 29 (n=103) | 83 ± 38 | 101± 62 |
bss apigenin (100mM) | 59 ± 21 (n=72)(p<0.22) | 68 ± 25 (p<0.0009)* | 84 ± 36 (p<.01)* |
bss kaempferol (100mM) | 59 ± 26 (n=68)(p<0.30) | 72 ± 34 (p<0.05)* | 85 ± 35 (p<0.03)* |
bss CPT (1mM) | 68 ± 30 (n=74)(p<0.40) | 79 ± 28 (p<0.56) | 78 ± 27 (p<0.004)* |
Mutants were reared in drug-containing food (chronic drug treatment) and tested for behavioral paralytic recovery times on 1, 2, and 3 days of age. MRT ± SD is shown with the number of flies tested indicated in parenthesis on 1d.
Asterisk (*) indicates a significance value of p < 0.05 compared with age-matched normal food control determined by Fisher's PLSD following ANOVA. Note that comparisons between different days may not be significant because the measurements are not completely independent. Note that because of lethality, CPT concentration is 1µM.