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Indicated that after HepG2 cells were transfected LV-siMAT2A, ALV-siMAT2β and LV-siMAT2A/2β respectively, compared with control Hepatic SAMe level was decreased by LV-siMAT2A (P < 0.01), and increased by LV-siMAT2β and LV-siMAT2A/2β (P < 0.01), but there was no difference between LV-siMAT2β and LV-siMAT2A/2β.
