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The proposed G protein-binding site of the BH domain. The domain is viewed from the same orientation shown in Fig. 4A. Residues Arg-151, Lys-187, Pro-270, and Arg-274 are conserved in the BH family. Leu-191 and Val-263 are nonconserved residues occurring at sites that are otherwise strongly conserved (Fig. 1). The side chains of Ile-267 and Met-271 are included to show the relatively hydrophobic character of this patch.
