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. Author manuscript; available in PMC: 2009 Jan 5.
Published in final edited form as: Pancreas. 2008 Mar;36(2):153–159. doi: 10.1097/MPA.0b013e318157753e

Figure 3. PI3K inhibitor wortmannin suppresses PDX-1 expression in remnant pancreas during pancreatic regeneration.

Figure 3

The effect of PI3K inhibition by wortmannin (Wort) on pAkt and PDX-1 expression in duct cells of remnant pancreas was assessed by immunohistochemistry as described in Fig. 1. Mice underwent partial Px and sacrificed 3 days after operation (n=3 per group). Arrow heads indicate typical pAkt or PDX-1 positive duct cell (magnification × 400). Arrows indicates pAkt-positive acinar cell. Slides were counterstained with hematoxylin.