Table 1.
Cell surface proteins monitored in figure 4 and their functions.
| Marker | Function |
|---|---|
| NK-T cell markers: | |
| NK1.1 | Marker expressed by NK and NK-T cells [36;37]. Present on C57BL/6 mice, but not on Balb/c. Expression is correlative to DX5 on C57BL/6 mice. |
| DX5 | Pan-NK marker that recognizes CD49b (alpha 2 integrin, very late antigen-2) [38]. Co-expressed with NK1.1 in C57BL/6 mice. |
| Molecules involved in memory responses: | |
| CD25 | IL-2 receptor alpha chain. Binds with high affinity to soluble IL-2 and acts in coordination with the beta-gamma receptor chains to initiate intracellular signals [44;45]. |
| CD44 | Adhesion molecule found on lymphocytes that is associated with memory T cells, up regulated during homeostatic proliferation and activation [40;41]. |
| CD62L | Adhesion molecule that is a member of the selectin family and is associated with memory T cell homing to the lymphoid organs [42;43]. |
| CD122 | IL-2/15 receptor beta chain, up regulated on memory phenotype T cells and during activation [26;39]. |