Table 4.

Distribution of ESR1 four-locus haplotype frequencies as estimated through EM algorithms among endometrial cancer cases and population controls

Locus				Proportion estimated to carry haplotype
rs2234693	rs9340799	rs4986934	rs1801132	Controls (n = 1560)	All cases (n = 694)	Endometroid cases (n = 647)
T	A	C	C	0.371	0.404	0.406
C	G	C	C	0.288	0.255	0.252
C	A	C	C	0.114	0.118	0.118
T	A	C	G	0.123	0.137	0.135
C	G	C	G	0.055	0.045	0.046
T	A	T	G	0.028	0.025	0.027
Proportion accounted for by the most common haplotypes:				0.979	0.984	0.984