Table 1.
Thirteen genes on PDGene top results list: numbers of related publications obtained by querying PDGene and Gene Prospector on 05/25/2008.
Gene |
No. Publications (Genetic Association Studies) |
|||
Total | Both | PDGene Only | Gene Prospector Only | |
GBA | 14 | 9 | 1 | 4 |
LRRK2 | 60 | 13 | 2 | 45 |
SNCA | 51 | 23 | 8 | 20 |
MAPT | 27 | 19 | 6 | 2 |
PINK1 | 20 | 9 | 2 | 9 |
CYP2D6 | 18 | 10 | 2 | 6 |
APOE | 33 | 13 | 2 | 18 |
MAOB | 21 | 17 | 2 | 2 |
ELAVL4 | 4 | 1 | 3 | 0 |
UCHL1 | 17 | 12 | 4 | 1 |
DRD2 | 19 | 7 | 3 | 8 |
GSTM1 | 11 | 6 | 1 | 4 |
SEMA5A | 4 | 1 | 3 | 1 |
Total | 299 | 140 | 39 | 120 |
Note: Literature published before 2001 was excluded. Literature with publication type "Letter" was excluded. The total number of PubMed publications reporting genetic associations with Parkinson's disease to May 25, 2008 was estimated as 299, the sum of totals in the Common (140), PDGene Only (39) and Gene Prospector Only (120) columns.