Figure 6.

TCF7L2 mRNA expression is overrepresented in parvocellular layers of monkey dLGN. A, Bright-field image of a Nissl-stained coronal section of monkey brain at the level of mid-dLGN. B, Image from a film autoradiogram illustrating in situ hybridization for TCF7L2 mRNA in a coronal section adjacent to that in A. TCF7L2 mRNA is mostly restricted to dorsal thalamus (DT) and shows prominent expression in dLGN. C, Higher power image of Nissl-stained dLGN showing the principal relay layers (1–6) and the S layers. D, Higher power image of a section adjacent to that in C showing TCF7L2 in situ hybridization. TCF7L2 mRNA expression is greater in the parvocellular layers (3–6) compared with magnocellular layers (1, 2). Hybridization to TCF7L2 mRNA is also observed in the S layers. E, Calibrated densitometric measures of film autoradiographs illustrate the enrichment for TCF7L2 hybridization in parvocellular layers compared with magnocellular layers. Measures are means ± SEM. *p < 0.01 (n = 5), ANOVA, post hoc Student's t test. Scale bars: (in B) A, B, 2 mm; (in D) C, D, 1 mm.