Table 6.
Correlation of mean mRNA expression of the five inhibitors of apoptosis family members with p53 for 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell carcinogenesis (linear regression analysis)
| Variable | By variables | Mean ± standard deviation | Correlation coefficients (r)* |
|---|---|---|---|
| p53 | 0.6173 ± 0.7992 | ||
| NAIP | 0.9168 ± 0.6198 | 0.9310 | |
| cIAP1 | 0.2871 ± 0.2004 | 0.8949 | |
| cIAP2 | 0.1235 ± 0.1227 | 0.8402 | |
| XIAP | 2.9527 ± 2.3436 | 0.7183 | |
| survivin | 0.9696 ± 0.9398 | 0.4847 |
cIAP1, cellular inhibitors of apoptosis protein 1; cIAP2, cellular inhibitors of apoptosis protein 2; NAIP, neuronal apoptosis inhibitory protein; XIAP, X-linked inhibitors of apoptosis protein.
*
P < 0.0001, linear regression analysis.