Figure 8.
Differential expression of genes describing mononuclear cell M1 and M2 subtypes in right ventricles at (a) day 1 (b) and week 6 after PE in comparison with time-matched vehicle-treated tissue. Fold changes are statistically significant using t-test with Benjamini and Hochberg adjustment for false discovery rates (n = 5 arrays/group). Gene symbols are CC chemokine ligand 20 also known as MIP-3α (Ccl20), CXC chemokine ligand 10 also known as IP-10 (Cxcl10), CC chemokine receptor 2 (Ccr2), major histocompatibility complex II (Fcgr2b), scavenger mannose receptors (Mrc1), macrophage galactose specific lectin 1 (CD301, Mgl1), platelet-derived growth factor receptor 1 (PDGFR1) and platelet-derived growth factor receptor beta polypeptide (PDGFRβ).