Figure 3.

Minimal inflammatory cell involvement by CD4 cells in septal interstitium of control (a) lung contrasts with noticeable CD4 cells in early BHT (b) group, in comparison with late (c) BHT. CD8 immunostaining in septal interstitium shows minimal infiltration in control (d) lungs and a more prominent involvement is present in early (e) compared with late (f) BHT group. The control (g) group shows a small amount of MAC-2 macrophages in alveolar spaces when compared with the more noticeable infiltration in early (h) and late (i) BHT group. Immunostaining for CD4 (a,b,c), CD8 (d,e,f) and MAC-2 (g,h,i) was carried out using 400×.