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. 2008 Jul 24;586(Pt 18):4465–4479. doi: 10.1113/jphysiol.2008.155143

Figure 8. The serotonergic facilitation of LTD induction is impaired in animals exposed to stress.

Figure 8

A, plot of normalized eEPSC amplitude subjected to 5-HT + tetani application in PFC neurons from stressed and control (non-stressed) rats. Note the diminished LTD induction in animals exposed to stress protocols (elevated platform and forced swim). Inset: averaged synaptic responses taken from the indicated time points. Scale bars: 50 pA, 10 ms. B, cumulative data (mean ±s.e.m.) showing the percentage reduction of eEPSC by 5-HT + tetani (measured at 50–60 min after washout) in PFC neurons from stressed and control rats. *P < 0.005, ANOVA.