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. 2008 Aug 28;586(Pt 20):5003–5012. doi: 10.1113/jphysiol.2008.158014

Table 2.

Brachial artery characteristics throughout an 8-weeks exercise intervention (n= 13) or control period (n= 7), measured at 2-week intervals

Week 0 Week 2 Week 4 Week 6 Week 8 ANOVA
Exercise training (n= 13)
 Diameter (mm) 4.2 ± 0.4 4.1 ± 0.6 4.0 ± 0.6 4.1 ± 0.4 4.3 ± 0.6 0.89
 FMD (%) 5.9 ± 1.9 9.1 ± 2.1* 8.4 ± 2.3* 7.6 ± 1.7 6.9 ± 2.4 0.001
 FMD (mm) 0.27 ± 0.06 0.31 ± 0.13 0.38 ± 0.18 0.31 ± 0.07 0.29 ± 0.19 0.12
 AUCSR 11596 ± 5236 19316 ± 13924 17759 ± 10655 15749 ± 7331 16730 ± 9341 0.42
 DC (%) 8.1 ± 1.4 9.2 ± 2.6* 9.9 ± 2.2* 10.4 ± 1.5* 10.5 ± 2.3* 0.02
 DC (mm) 0.35 ± 0.12 0.37 ± 0.07 0.40 ± 0.10 0.37 ± 0.07 0.41 ± 0.13 0.40
 Resting flow (ml min−1–1) 63 ± 28 62 ± 39 63 ± 41 64 ± 27 64 ± 17 0.99
 Peak RH flow (DC) (ml min−1–1) 497 ± 313 616 ± 232 578 ± 255 648 ± 274 634 ± 248 0.47
 Flow AUC (DC) (ml s−1) 606 ± 247 656 ± 318 645 ± 315 651 ± 341 651 ± 281 0.95
Controls (n= 7)
 Diameter (mm) 4.2 ± 0.7 4.3 ± 0.4 4.2 ± 0.9 4.3 ± 0.3 4.1 ± 0.9 0.71
 FMD (%) 6.8 ± 2.1 7.3 ± 3.2 6.9 ± 1.0 6.8 ± 2.4 6.8 ± 1.2 0.99
 FMD (mm) 0.27 ± 0.66 0.26 ± 0.10 0.27 ± 0.13 0.28 ± 0.07 0.24 ± 0.10 0.91
 AUCSR 17602 ± 11185 16303 ± 11924 15158 ± 20926 15324 ± 5203 15415 ± 12568 0.99
 DC (%) 8.7 ± 3.6 9.1 ± 2.9 9.0 ± 3.1 9.2 ± 2.9 9.4 ± 3.0 0.99
 DC (mm) 0.32 ± 0.10 0.33 ± 0.10 0.37 ± 0.12 0.37 ± 0.01 0.32 ± 0.01 0.24
 Resting flow (ml min−1) 65 ± 27 64 ± 26 64 ± 42 64 ± 10 64 ± 17 0.99
 Peak RH flow (DC) (ml min−1) 506 ± 200 508 ± 170 506 ± 244 508 ± 186 508 ± 150 1.00
 Flow AUC (DC) (ml s−1) 616 ± 255 613 ± 258 618 ± 419 612 ± 150 612 ± 162 1.00
*

Significant from baseline at P < 0.05. Values are means and ±s.d.; s.d., standard deviation; n, no of subjects; FMD, flow-mediated dilatation; AUCSR, shear rate area under the curve; DC, dilator capacity; RH, reactive hyperemia