Table 2.
Brachial artery characteristics throughout an 8-weeks exercise intervention (n= 13) or control period (n= 7), measured at 2-week intervals
Week 0 | Week 2 | Week 4 | Week 6 | Week 8 | ANOVA | |
---|---|---|---|---|---|---|
Exercise training (n= 13) | ||||||
Diameter (mm) | 4.2 ± 0.4 | 4.1 ± 0.6 | 4.0 ± 0.6 | 4.1 ± 0.4 | 4.3 ± 0.6 | 0.89 |
FMD (%) | 5.9 ± 1.9 | 9.1 ± 2.1* | 8.4 ± 2.3* | 7.6 ± 1.7 | 6.9 ± 2.4 | 0.001 |
FMD (mm) | 0.27 ± 0.06 | 0.31 ± 0.13 | 0.38 ± 0.18 | 0.31 ± 0.07 | 0.29 ± 0.19 | 0.12 |
AUCSR | 11596 ± 5236 | 19316 ± 13924 | 17759 ± 10655 | 15749 ± 7331 | 16730 ± 9341 | 0.42 |
DC (%) | 8.1 ± 1.4 | 9.2 ± 2.6* | 9.9 ± 2.2* | 10.4 ± 1.5* | 10.5 ± 2.3* | 0.02 |
DC (mm) | 0.35 ± 0.12 | 0.37 ± 0.07 | 0.40 ± 0.10 | 0.37 ± 0.07 | 0.41 ± 0.13 | 0.40 |
Resting flow (ml min−1–1) | 63 ± 28 | 62 ± 39 | 63 ± 41 | 64 ± 27 | 64 ± 17 | 0.99 |
Peak RH flow (DC) (ml min−1–1) | 497 ± 313 | 616 ± 232 | 578 ± 255 | 648 ± 274 | 634 ± 248 | 0.47 |
Flow AUC (DC) (ml s−1) | 606 ± 247 | 656 ± 318 | 645 ± 315 | 651 ± 341 | 651 ± 281 | 0.95 |
Controls (n= 7) | ||||||
Diameter (mm) | 4.2 ± 0.7 | 4.3 ± 0.4 | 4.2 ± 0.9 | 4.3 ± 0.3 | 4.1 ± 0.9 | 0.71 |
FMD (%) | 6.8 ± 2.1 | 7.3 ± 3.2 | 6.9 ± 1.0 | 6.8 ± 2.4 | 6.8 ± 1.2 | 0.99 |
FMD (mm) | 0.27 ± 0.66 | 0.26 ± 0.10 | 0.27 ± 0.13 | 0.28 ± 0.07 | 0.24 ± 0.10 | 0.91 |
AUCSR | 17602 ± 11185 | 16303 ± 11924 | 15158 ± 20926 | 15324 ± 5203 | 15415 ± 12568 | 0.99 |
DC (%) | 8.7 ± 3.6 | 9.1 ± 2.9 | 9.0 ± 3.1 | 9.2 ± 2.9 | 9.4 ± 3.0 | 0.99 |
DC (mm) | 0.32 ± 0.10 | 0.33 ± 0.10 | 0.37 ± 0.12 | 0.37 ± 0.01 | 0.32 ± 0.01 | 0.24 |
Resting flow (ml min−1) | 65 ± 27 | 64 ± 26 | 64 ± 42 | 64 ± 10 | 64 ± 17 | 0.99 |
Peak RH flow (DC) (ml min−1) | 506 ± 200 | 508 ± 170 | 506 ± 244 | 508 ± 186 | 508 ± 150 | 1.00 |
Flow AUC (DC) (ml s−1) | 616 ± 255 | 613 ± 258 | 618 ± 419 | 612 ± 150 | 612 ± 162 | 1.00 |
Significant from baseline at P < 0.05. Values are means and ±s.d.; s.d., standard deviation; n, no of subjects; FMD, flow-mediated dilatation; AUCSR, shear rate area under the curve; DC, dilator capacity; RH, reactive hyperemia