Table 1.

Order and identity of genomes deletions for the 30 permutations depicted in Figure 1. Genomes are in decreasing order from largest to smallest outlier. Phylogenetic profiles for a given genome set were grouped into biological processes defined by gene ontology; a pairwise distance matrix was then generated to identify the outlier genome (no ties were discovered). To evaluate the affect of size and composition on the power of a phylogenetic profile to predict function, outlier genomes were removed one-by-one until the size of the genome set equaled 2, i.e. composed of just Hsa and Mus.

Ciona intestinalis	Cint
Apis mellifera	Ame
Caenorhabditis elegans	Cel
Anopheles gambiae	Aga
Strongylocentrotus purpuratus	Spu
Saccharomyces cerevisiae	Sce
Arabidopsis thaliana	Ath
Drosophila melanogaster	Dme
Saccharomyces paradoxus	Spa
Candida glabrata	Cgl
Candida albicans	Cal
Schizosaccharomyces pombe	Spo
Saccharomyces bayanus	Sba
Saccharomyces castellii	Sca
Gallus gallus	Gga
Danio rerio	Dre
Tetraodon nigroviridis	Tni
Fugu rubripes	Fru
Saccharomyces kudriavzevii	Sku
Macaca mulatta	Mmu
Xenopus tropicalis	Xtr
Saccharomyces kluyveri	Skl
Pan troglodytes	Ptr
Monodelphis domestica	Mdo
Saccharomyces mikatae	Smi
Canis familiaris	Cfa
Rattus norvegicus	Rno
Bos taurus	Bta
Encephalitozoon cuniculi	Ecu
Homo sapiens	Hsa*
Mus Musculus	Mus*