Skip to main content
. Author manuscript; available in PMC: 2009 Oct 23.
Published in final edited form as: Neuron. 2008 Oct 23;60(2):343–352. doi: 10.1016/j.neuron.2008.10.002

Figure 6. Recovery of EPSC amplitudes from depression is slow and monoexponential.

Figure 6

A, Vestibular afferents were stimulated with conditioning trains of 20 pulses at 10, 50, or 100 Hz, followed by a test pulse at a variable time afterwards. B, Recovery from depression was best fit with a single exponential. The tau of recovery was similar across the three conditioning frequencies of 10, 50, and 100 Hz (2.2, 2.5, and 1.9 s respectively; n = 5). C, EPSCs did not recover in amplitude during shorter intervals (10–100 ms, all tested with 50 Hz conditioning train). Application of 100 µM EGTA-AM for 5 min had no effect on recovery (n = 4). D, EGTA-AM had no effect on the timecourse of recovery for longer test intervals (conditioning train, 50 Hz; n = 7).