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. Author manuscript; available in PMC: 2009 Jan 6.
Published in final edited form as: Mucosal Immunol. 2008 Mar 5;1(3):229–238. doi: 10.1038/mi.2008.1

Figure 9.

Figure 9

Ligation of TREM-2 by LOS induces IL-6 production in HeLa cells. HeLa cells were treated with LOS from strain 1291 at concentrations of 10 and 100 ng/ml for 12 hours. Control wells were treated with culture media only. For some experiments, cells were treated with affinity-purified goat anti-human TREM-2 polyclonal IgG prior to addition of the LOS. Supernatants from the LOS-treated and untreated cells in the presence and absence of anti-human TREM-2 were assayed for IL-6 by ELISA. The bars represent the mean of quadruplicate data points and the error bars are ±SEM. The results are representative of three independent experiments. Statistical comparisons: *, p > 0.1; **, p < 0.05; ***, p < 0.05.